Unfortunately on day four of PEX the platelet count falls to 19, LDH rises and he spikes a temperature. Antibiotics for presumed sepsis are started. PEX is increased to BD with no improvement in platelet count and he starts to become confused again. Steroids are re-started and PEX is continued BD.
Rituximab has been mentioned by the team. Is this everyone’s first line? What abor ciclosporin or vincristine?
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