You are the Haematology registrar oncall.  A GP contacts you for advice.  He has reviewed a 55 yr old gentleman, who had initially presented with some difficulty swallowing.  However during the consultation the patient had suggested that he had been quite lethargic, and SOB on exertion.  The GP had performed some basic blood tests.

• HB 67 g/l (ref 130-180)
• MCV 95fL (ref 82-98)
• WCC 2.8×10*9/L (ref  4-11)
• Platelets 140×10*9/L (ref 150-450)

What further tests would you advise?

Differential diagnosis?

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