Case 9 – update 4

*For start of case see  The rest of the updates are below*

The biopsy results from our patient with mediastinal mass have returned.  The histology is in keeping with primary mediastinal B cell lymphoma.

Hep B and C are negative.  Urate is normal.  A bone marrow aspirate and trephine biopsy have been performed which reveal no involvement by lymphoma.  A PET scan is requested and will be done within the next day or so.

There is a risk of SVCO and you want to start therapy within the next few days.  Allopurinol is started to prevent tumour lysis syndrome.


  • What treatments do you know of for primary mediastinal B cell lymphoma?
  • What is your preferred treatment and why?

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