Case 15 – update 5

Bone marrow aspirate confirms your suspicion.  Blast count >60%.

Flow cytometry results:

CD2 – 12%

CD 3-8%

CD7 – 12%

CD10-86%

CD13-2%

CD19-60%

CD33-1%

CD34-71%

CD64-2%

hla-dr-76%

TDT- 47%

cd79a- 87%

What would these markers suggest?

In the UK which trial would you consider for this patient? what induction treatment would be indicated in this case?

Cytogenetics samples were sent with the marrow, and are awaited.  Which cytogenetic abnormalities would suggest high risk disease?

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