Case 16 – update 5

The start of case 16 can be found by scrolling down or by clicking a link to the right hand side.

Common causes of hepatosplenomegaly include:

  • Hepatitis
  • Rubella
  • Malaria
  • Leishmaniasis
  • Parasitic infection
  • Myeloproliferative neoplasms
  • Leukaemia
  • Lymphoma
  • Haemoglobinopathies
  • Metabolic diseases including Gaucher’s
  • Chronic liver disease and portal hypertension (any cause)
  • Amyloidosis
  • Acromegaly
  • Systemic lupus erythematosus
  • Sarcoidosis

After review by haematology a bone marrow aspirate and trephine biopsy is performed to look for any haematological cause of hepatosplenomegaly and for culture.  Below is a few pictures:




  • What do you see?
  • Is there a unifying diagnosis?

Please reply on Twitter and always include #teamhaem to allow others to follow your comments. Please join in the debate and learn about haematological problems along the way. The case will continue to  evolve over the coming week so keep checking #teamhaem for more information.

Please note – all cases on TeamHaem are entirely fictional to protect patient confidentiality.

TeamHaem are not a position of authority.  It is an educational platform to allow discussion

About TeamHaem

Online education and discussion about all things haematological
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