Case 19 – update 4

For the start of the case scroll below… or click

Our team have come up with some good points.

  • Could a paroxysmal haemoglobinuria clone has occurred causing haemolysis
  • Haemolysis can rarely be associated with myelodysplasia

The patient now has symptomatic anaemia and the team feel a transfusion is needed.  A group and antibody screen is sent and the lab call to say that the antibody screen is now positive as well as a DAT.  The previous antibody screens had been negative and she is group A RhD positive.


  • Does this have implications for transfusion?
  • What has happened to the patient?

Please reply on Twitter and always include #teamhaem to allow others to follow your comments. Please join in the debate and learn about haematological problems along the way. The case will continue to  evolve over the coming week so keep checking #teamhaem for more information.

Please note – all cases on TeamHaem are entirely fictional to protect patient confidentiality.

TeamHaem are not a position of authority.  It is an educational platform to allow discussion

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Online education and discussion about all things haematological
This entry was posted in Anaemia, Bone marrow failure, Transfusion and tagged , . Bookmark the permalink.

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