#TeamHaem correctly identified the main abnormalities in the film:
- Tear drop poikilocytes
- Leucoerythroblastic features (left shifted granulocytes and nucleated red cells)
The patient had splenomegaly and was suffering from weight loss and subjective fevers.
Questions:
- Name three possible causes of the blood film features
- Taking into account the clinical information what is the likely diagnosis and what tests can be done to confirm?
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Primary myelofibrosis
BM infiltration with leukemia, lymphoma or non hemopietic cells
Thanks for all of your useful comments. We try to do most of the discussion via Twitter – next time reply to us and use #teamhaem! Thanks!