Case 56 – update 2

The biopsy shows an angiocentric distribution of atypical lymphoid cells penetrating the blood vessel walls.The immunophenotype shows CD2 +, Surface CD 3 -, Cytoplasmic CD3 + and CD 56 + cells.

James’ biopsy confirms a diagnosis of Nasal NK/T cell lymphoma. James has an ECOG 0, LDH is 120 (Normal) and has a PET CT scan that confirms stage II disease. His EBV PCR is now back and is 4 x10^3 and EBER studies demonstrate EBV positivity of the nasal lesion.

What is his IPI score?

Does IPI have prognostic information in the context of NK cell lymphoma?

What are his treatment options?

 

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