Our patient has undergone emergency surgical decompression for severe C3/4 spinal cord compression secondary to a lesion in his C3 vertebral body. He is recovering well on the neurosurgical ward.
Initial investigations were unremarkable.
Following discussion, the further investigations below were requested and all found to be within their normal ranges:
Serum calcium, immunoglobulins, serum electrophoresis, serum free light chains, beta 2 microglobulin, LDH, HIV, Hepatitis B, Hepatitis C.
Histopathology have called through a provisional report, our patient’s C3 biopsy is ‘highly suspicious for plasmacytoma’.
- What histopathological features would support a diagnosis of plasmacytoma?
- How would you prioritise further investigations for our patient? Why?
- How would you explain this result to our patient?
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