Case 97 – update 2

The bone marrow aspirate did appear to show an excess of Plasmacytoid and lymphoplasmacytoid cells.

Immunophenotype results:

Abnormal population: Kappa restricted B cell population = 18% of total nucleated cells.

Immunophenotype: CD19+, CD5 negative, CD23 negative/wk, CD10 negative, CD103 negative, CD11c+/-, CD38+/-, FMC7+, CD79b+, sIg++ (CLL score 0/5)

What are your thoughts regarding the possible diagnosis?

What other molecular test could be performed on the bone marrow that could assist in diagnosis?

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