Case 98 – part 2 – update 1

We have confirmed progression in our patient’s CLL.

There is no evidence of haemolysis.

He has a pmh of HTN, diabetes, mild copd and osteoarthritis which limits his mobility. He has an ecog of 2 (was 1 prior to the progression of his cll and resultant fatigue).

He has been started on chloramucil and obinituzumab however during the first obinutuzumab infusion he develops pyexia, and rigors.

  • What do you think is happening?
  • What would you do?

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