Case 101 – update 1

She is given prothrombin complex concentrate and vitamin K 10mg IV.

She has a history of asthma and depression, she has taken sertraline for the last five weeks and salbutamol inhalers infrequently.  There is no history of anticoagulant use and no previous history of abnormal bleeding.

Her pre-treatment factor levels return as:

Factor II – 11%                      Factor VII – 18%

Factor X – 7%                        Factor V – 101%

Factor VIII – 156%                Factor IX – 2%

Liver and renal function are normal.

Peripheral blood morphology is normal.

D-dimer is 350 ng/mL

A pregnancy test is negative.

Questions:

How do you interpret these results?

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