Case 108 – Update 4!

Our patient achieved complete metabolic remission following #6 R-CHOP chemotherapy for his relapsed advanced stage NLPHL.

Unfortunately 18 months after completing treatment he attended with drenching night sweats, intermittent fevers and marked malaise. His spleen was palpable just below the costal margin but examination was otherwise unremarkable. A biopsy is pending following his repeat PET scan (see image below):



  1. What is the most likely diagnosis? What risk factors were there for this?
  2. What further investigations would you want to perform?


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