Case 121 – The Beginning!

Welcome to another TeamHaem clinical case! Get involved and help shape the care of our fictional patient……

You review a 48 year old patient in lymphoma clinic. She was diagnosed with stage IVA diffuse large B cell lymphoma (DLBCL), with no evidence of MYC rearrangement, and completed treatment with six cycles of R-CHOP. End-of-treatment PET-CT demonstrated complete metabolic remission (CMR).

6 months following this she re-presented with stage IV relapsed disease and is currently post 2 cycles of R-GDP as ‘salvage chemotherapy.’ On review of a CT scan to assess disease response, she has progressive disease. She has no significant co-morbidity and ECOG performance status is 0.

What are the treatment options for this lady? Would you arrange any further investigations at this point?


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