Case 129 – update 1

Thanks for everyone’s thoughts So far we have now established the following:

No Anticoagulants
No ETOH excess
Normal liver function
No previous coagulation results available for this lady
No personal history of bleeding
No FHx of bleeding disorder

The lab performed the following extra tests at your request:

Repeat Coag results:

PT 12.4, APTT 49.6, APTT 50:50 Mix 46, Fib 2.9, DRVVT Ratio 1.5 (0.8-1.2)

Anticardiolipin and Anti beta 2 glycoprotein 1 Ab are pending
What is the likely cause for prolonged APTT?
Is it safe to proceed with planned LP on the basis of the above tests?
Anything further to recommend to the clinical team?

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