Case 131 – update 2

Peripheral blood flow cytometry identifies a population of cells (44% of total nucleated cells) with the following immunophenotype:

CD19+, CD5 negative, CD200 negative, CD10 weak, FMC7+, CD23 negative, CD38+, CD11c negative, CD103 negative, CD20+, sIg+ (lambda-restricted), CD34 negative, nTdT negative


What is the most likely diagnosis and how would you confirm it?

Given the most likely diagnosis, what further investigations are required prior to starting treatment?


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