Case 132 – Update 3!

Thank you for everyone’s input and you’ve all correctly noted the blood film findings of consistent of abnormal population of predominantly mature lymphocytes (prolymphocytes only 10%) inkeeping with a lymphoproliferative disorder and genuine thrombocytopenia.

The flow cytometry is as follows:

CD3-, CD5+, CD10+, CD19+, CD23+, CD79b weak, FMC7-, Igs+/-.

Questions:

  1. What is the diagnosis?
  2. What cytogenetic abnormalities would help you to prognosticate?
  3. What other baseline investigations would you request?

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