Thank you for everyone’s input and you’ve all correctly noted the blood film findings of consistent of abnormal population of predominantly mature lymphocytes (prolymphocytes only 10%) inkeeping with a lymphoproliferative disorder and genuine thrombocytopenia.
The flow cytometry is as follows:
CD3-, CD5+, CD10+, CD19+, CD23+, CD79b weak, FMC7-, Igs+/-.
Questions:
- What is the diagnosis?
- What cytogenetic abnormalities would help you to prognosticate?
- What other baseline investigations would you request?
Please reply to us (@TeamHaem) on Twitter and always include #TeamHaem to allow others to follow your comments. Please join in the debate and learn about haematological problems along the way. The case will continue to evolve over the coming week so keep checking #TeamHaem on Twitter for more information.
Please note – all cases on TeamHaem are entirely fictional to protect patient confidentiality.
TeamHaem are not a position of authority. It is an educational platform to allow discussion and learning.