Thank you for your ongoing input.
Unfortunately the investigations performed to assess our patients new onset B symptoms and mild lymphocytosis whilst on acalabrutinib have revealed that he has diffuse large B cell lymphoma:
- LDH: 1200
- CT: widespread mild lymphadenopathy (predmoninantly <3cm) and a large 8cm mass in retroperitoneum
- PETCT: Retroperitoneal mass and intrabdominal nodes significantly more FDG avid than other other low volume lymphadenopathy (SUV max 15).
- Retroperitoneal mass histology: DLBCL
- What further investigations/additional information would you want to acertain?
- How would you manage this patient?
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