Author Archives: TeamHaem

Thank you for the ongoing contributions to our case! Our patient achieved a complete response following radiotherapy treatment alone (30Gy) and remained under haematology follow-up. Unfortunately 5 years later he attends the haematology clinic earlier than scheduled as he has … Continue reading →

Thank you for everyone’s contributions in obtaining the diagnosis of Nodular Lymphocyte-Predominant Hodgkin Lymphoma (NLPHL)! The lymph node morphology demonstrates large atypical cells with multiple nucleoli (lymphocyte-predominant cells) embedded within follicles. The IHC is as follows: Lymphocyte-predominant cells:CD20+, CD45+, CD75+, … Continue reading →

Thank you to all the contributions so far! We have now established that our 32 year old mans neck mass has been gradually increasing in size since he noted it 6 months ago. He has otherwise been well in himself … Continue reading →

Thank you to all the contributions so far! We have now established that our 32 year old mans neck mass has been gradually increasing in size since he noted it 6 months ago. He has otherwise been well in himself … Continue reading →

You review a 32 year old man in outpatients who has been referred for a neck lump. On examination he has a 2cm cervical lymph node which he originally noticed approximately 6 months ago. He has had no night sweats … Continue reading →

Thank you for your contribution in this week’s #teamhaem case. This week we have been looking at Transient Leukaemia of Down Syndrome (TL-DS). Background Between 5%- 30% children with Down syndrome (DS) are born with Transient Leukaemia of Down syndrome … Continue reading →

CXR and ECHO show no significant abnormalities. Abdo USS confirms hepatosplenomegaly but no ascites. There are no skin rashes and his blood tests are stable. Blood film report: Polycythaemic film. Pleomorphic blasts with evidence of cytoplasmic blebbing. Manual blast count … Continue reading →

You think the baby has some dysmorphic features. You look at his blood film. You also check his conjugated bilirubin and request CXR, abdominal USS and ECHO. Questions: 1. What are the main features and why? 2. What factors might … Continue reading →

You meet the baby with his mother. He was a little floppy at birth and not feeding well with a low grade fever. He is on 2L oxygen but with no respiratory distress. He is visibly jaundiced. The mother is … Continue reading →

Welcome to our new #TeamHaem case. You are the haematology registrar. You get a phone call from a junior doctor on the neonatal ward. They have a 2 day old baby boy with jaundice. The baby seems stable, though he … Continue reading →

Thank you all for your contributions this week.   We focused on a patient with a new diagnosis of primary immune thrombocytopenia (ITP), please refer to TeamHaem case 11 for a full summary of this condition.   In the wake … Continue reading →

Our patient is in haematology outpatient clinic. We have excluded any secondary causes for an isolated thrombocytopenia and are considering first line therapy with prednisolone 1mg/kg/day with gastric protection (our local #TeamHaem preference). We have considered the potential risks of … Continue reading →

You are checking the results from yesterday’s surgery and review our patients consultation notes: 61 year old female, previously fit and well ·        Easy bruising over both lower limbs for 2-3 weeks. No constitutional symptoms ·        No significant past medical history ·        No … Continue reading →

Welcome to our new #TeamHaem case! You are working in a GP surgery. You see from your urgent surgery list that the next patient has registered with the practice within the last 24 hours and has told the receptionist she … Continue reading →

Our patient was discussed at MDT and as many have suggested, he is treated with intensive chemotherapy. MATRIX – HD MTX, cytarabine, thiotepa and rituximab is the current regime recommended in the UK.  Intrathecal chemotherapy is not advocated in the BSH … Continue reading →

MRI performed at the tertiary centre showed no evidence of a cerebral lesion.  You therefore plan with the neurosurgical team to stop the steroids and repeat the MRI after a short interval (2-4 weeks) whilst monitoring the patient closely.   … Continue reading →

Welcome back! During your on call as the haematology registrar on the 2nd January you are contacted by the neurosurgical team.  A 54 year gentleman had been referred into the tertiary centre from a local hospital over the Christmas holidays.  … Continue reading →

Primary CNS lymphoma   1% of all non Hodgkin lymphomas, 3 % of all brain tumours.  It may [resent with a range of symptoms including focal motor deficits and behavioural change as seen in the patient in this case.   … Continue reading →

Thankyou for taking part in our Christmas quiz! Here are the questions and answers! 1. Which animals have: • Blue blood • Green blood • Yellow blood 2. The Japanese traditionally associate blood groups with personality. Can you match them … Continue reading →