Category Archives: Acute leukaemia
Paediatric ALL In this case, our child presented with a petechial rash. This can present with a number of different diagnosis therefore a wide differential needs to be formed. This includes: HSP – Usually a classical distribution of purpura, bruising … Continue reading
Bone marrow aspirate confirms your suspicion. Blast count >60%. Flow cytometry results: CD2 – 12% CD 3-8% CD7 – 12% CD10-86% CD13-2% CD19-60% CD33-1% CD34-71% CD64-2% hla-dr-76% TDT- 47% cd79a- 87% What would these markers suggest? In the UK which … Continue reading
As suggested the blood film is suspicious of leukaemia. You obviously at admit the child for further investigation. You recognise the risk of tumour lysis. You decide to go ahead and perform a bone marrow under sedation. What other investigations/examinations … Continue reading
You had a right to be worried! This is what you find on the peripheral blood smear. What can you conclude from this small section of film. What would you do now?
The FBC is ordered that day. One of the laboratory staff calls the GP with the results. Hb 91 g./l WCC 5.6 x10*9 neut 1.3×10*9 plt 7 x 10*9 what is your differential now? Concerns for this patient? Further investigations
Can you describe the rash? On further questioning – the patient has not had a fever and there is no arthalgia. Obviously the GPs first concern is meningitis, however on review there are no signs of meningism. His mother thinks … Continue reading