Category Archives: Haemoglobinopathy
Welcome back to #teamhaem. Great you have you on board with this new case. We start in the emergency department. A 16 year old female with known homozygous sickle cell anaemia presents to your hospital with abdominal pain and feeling lightheaded. … Continue reading
The patient’s blood film shows target cells, sickle cell, Howell Jolly bodies. It is difficult to say what the underlying condition is other than a sickling syndrome with hyposplenism. Target cells are often found in all of these disorders, but … Continue reading
This is the last installment of our morphology week. Name three things important in the management in this patient: Please reply on Twitter and always include #teamhaem to allow others to follow your comments. Please join in the debate and … Continue reading
A blood film has been made from the following patient with the clinical details ‘SOB’. This is the first time you have seen the patient in your hospital. Questions How do you report the film? Who else should you inform of … Continue reading
Slide 1 Answer: Bernard Soulier syndrome, bleeding disorder characterized by thrombocytopenia and large platelets. Autosomal recessive inheritance. Presentation consistent with low or dysfunctional platelets and include easy bruising, nosebleeds, mucosal bleeding, menorrhagia, and, occasionally, GI bleeding. Slide 2 Answer: Hairy cell leukaemia. … Continue reading
Sickle cell disease Obviously, in most circumstances the patient would be able to inform the medical team that they have a history of sickle cell disease – but to make this case interesting – the diagnosis was not revealed immediately!!! … Continue reading
HPLC is performed for this patient. Can anyone described the results? What is HPLC? What does it detect? What are the other forms of sickle cell?
So you have established that this patient has sickle cell disease. She is currently visiting a friend in the area so she had never attended this hospital before. Her pain has been controlled temporpraily with IV morphine, however you are … Continue reading
The haemtology registrar is contacted and asked to review the patients blood film. There are at least five features on this film to identify the underlying diagnosis!