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Category Archives: Laboratory morphology
Case 54 – case A
This week we are going to look at a range of short cases, some of which are morphology based, and most will include MCQ questions. The discussion does not have to be limited to the basic answer – please feel … Continue reading
Posted in Chronic leukaemia, Laboratory morphology, Lymphoma
Tagged Flow cytometry, Lymphocytosis, morphology
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Case 50 part 4 – summary
The laboratory data of anaemia, thrombocytosis, a leucoerythroblastic film and tear drop poikilocytes point towards a diagnosis of myelofibrosis. Other causes of a leucoerythroblastic film with tear drop poikilocytes may include: Beta thal intermedia/major (this should be obvious from the … Continue reading
Case 50 part 4 – update
#TeamHaem correctly identified the main abnormalities in the film: Tear drop poikilocytes Leucoerythroblastic features (left shifted granulocytes and nucleated red cells) The patient had splenomegaly and was suffering from weight loss and subjective fevers. Questions: Name three possible causes of … Continue reading
Posted in Laboratory morphology, Myeloproliferative neoplasm
Tagged Blood film, leucoerythroblastic, Myelofibrosis
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Case 50 part 4 – the beginning
You are the GP reviewing a patient. He has indigestion and looks pale. A FBC is done: Hb 92g/L (115-160) MCV 76fL (79-98) WCC 15.6×10*9/L (4-11) Neuts 12.6×10*9/L (2-7) PLT 578×10*9/L (150-400) Here is the blood film: Questions: Describe … Continue reading
Case 50 part 3 – summary
It just goes to show that picking up on simple signs can lead to the start of a diagnostic journey. The patient with the film below (second from left) had a FBC as she had suffered from back pain and … Continue reading
Posted in Laboratory morphology, Myeloma/paraproteins
Tagged Blood film, myeloma, Paraprotein
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Case 50 part 3 – the beginning
You are reviewing the blood films from today. Can you make a diagnosis without a microscope? Please reply to us (@TeamHaem) on Twitter and always include #TeamHaem to allow others to follow your comments. Please join in the … Continue reading
Posted in Laboratory morphology, Myeloma/paraproteins
Tagged Blood film, myeloma, Paraprotein
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Case 50 part 2 – summary
In haematology it is important integrate laboratory investigations to clinical presentations. A blood transfusion was requested in a young patient with macrocytic anaemia with no previous blood count information. The blood film was reviewed rapidly: The diagnosis of a … Continue reading
Case 50 part 2 – the beginning
A 21 year old female presents with chest pain. You are asked to authorise a blood transfusion as she is anaemic. Hb 69g/L (115-160) MCV 111fL (79-98) WCC 12.6×10*9/L (4-11) Neuts 10.6×10*9/L (2-7) PLT 578×10*9/L (150-400) Here is her blood … Continue reading
Case 50 part 1 -summary
Thanks for all of the contributions. The marrow showed erythrophagocytosis. This can be a sign of autoimmune haemolytic anaemia. In particular it can be seen in paroxysmal cold haemoglobinuria. We were slightly mean and didn’t show the rest of the … Continue reading
Case 50 part 1 – update
We were reviewing the marrow smear from an elderly gentleman with weight loss and macrocytic anaemia. Further results include: Reticulocyte count 276×10*9/L Bilirubin 54ug/L LDH 1056U/L DAT IgG 4+ The above is consistent with warm autoimmune haemolytic anemia. The … Continue reading
Case 50 part 1 – the begining
This week we will be doing some short cases based around some pictures. Each case will last around 24-36 hours, so get in quick! As always – the information is posted here and the discussion will be on Twitter. Follow … Continue reading
Case 44 – the beginning
Welcome to case 44! Share your thoughts on the following blood film. What other information would you wish to know following review of the film? What advice would you give to the referring clinical? Would you request any further investigations … Continue reading
