Category Archives: Paediatric haematology

Case 67 – part 3 summary

Thankyou for all your help this week. This week we had a quick look at 3 causes for anaemia in children, although there are obviously many more! For our final case this week we had a young boy who had … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , , , ,

Case 67 – part 3

And here we have our 3rd and final case A 4 year old boy who is normally well has been bought to A&E by his dad. He has been unwell for the last few days, and dad thinks he is … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , , , ,

Case 67 – part 2 summary

We have found that our patient has PCH. PCH is a form of auto immune haemolytic anaemia which will usually present in young children. It is caused by a biphasic antibody with will usually target the P antigen on red … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , , ,

Case 67 – part 2

Here we have our second case! A 5 year girl old presents to her A&E with her grandmother. She had been the park today and has now become generally unwell with abdominal pain, back pain, vomiting and feeling shivery. HB … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , , , ,

Case 67 – part 1 summary

So we have found our patient has g6pd deficiency precipitated by eating broad beans. With folic acid and supportive care he made a full recovery. G6pd deficiency is an X linked disorder that results in a deficiency of the enzyme … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , ,

Case 67 – part 1

Welcome to our cases this week. This week we will be focusing on children, with 3 short cases. Our first case begins in A&E. We have a 3 year old boy who’s  mum has bought him in because he has … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , ,

Case 63 – summary

Thanks to everyone who has taken part in this week’s case. It focused on childhood anaemia and it’s investigations. See a link to our Storify of this week’s case https://storify.com/TeamHaem/case-63-a-pale-child   Childhood anaemia There are a number of causes of anaemia … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , , , , , , , , , ,

Case 63 – update 4

Our four year old appears to have acute parvovirus infection. It commonly causes reduced rd cell production but this is generally only significant in patients with increased red cell destruction, who rely on a very active marrow e.g. inherited and … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , , , , , , , , , ,

Case 63 – update 3

Our four year old has spherocytes on the blood film. These are seen in various types of haemolytic anaemias – mainly autoimmune haemolysis and hereditary spherocytosis. There is a lack of polychromasia reflecting the lack of marrow turnover and linking … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , , , , , , ,

Case 63 – update 2

Our four year old has been having fever and is pale. A blood count showed: Hb 45g/l (115-145g/l) MCV 85fL WCC 12×10*9/l (5-15×10*9/l) with normal white cell differential Platelets 352×10*9/l (150-450×10*9/L) Reticulocytes 5×10*9/l (50-100×10*9/l)   A blood film is requested and … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , , , , , , ,

Case 63 – update 1

We have a pale four year old boy who appears to be generally unwell with occasional fever and sore throat. On examination his observations show a tachycardia of 140bpm and respiratory rate of 35rpm. There is no menginism. There are … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , , , ,

Case 63 – the beginning

You are a general practitioner and are reviewing a four year old boy. His mother is worried that he is looking rather pale and has been unusually tired and off his food. He has a sore throat and occasional fever over … Continue reading

Posted in Anaemia, Paediatric haematology | Tagged , , ,

Case 60 – summary

Panel: In this case we interpreted an antibody panel to establish this lady was A RhD positive and had an anti K antibody. When a possible antibody is detected it is important to phenotype the patient’s cell for the corresponding … Continue reading

Posted in Paediatric haematology, Related to other specialities, Transfusion | Tagged , , , , ,

Case 60 – update 3

The IUT thankfully was performed without complication and the fetal medicine team repeated the IUT two weeks later and the delivery is then arranged. When planning for delivery what bloods should be taken from the cord sample? What are the … Continue reading

Posted in Paediatric haematology, Related to other specialities, Transfusion | Tagged , , , , ,

Case 60 – update 2

The patient has being having regular antibody titres every four weeks and her titre remains 1 in 8. Her weekly MCA dopplers unfortunately shown at 26 weeks her MCA velocity has increased >  1.5 multiples of median suggestive of fetal … Continue reading

Posted in Paediatric haematology, Related to other specialities, Transfusion | Tagged , , , , ,

Case 60 – update 1

The lady is Group A positive and has an Anti K antibody detected.The lab performed phenotyping on the maternal sample and she is K negative. She has never been pregnant before. She has no history of IV drug abuse. She … Continue reading

Posted in Paediatric haematology, Related to other specialities, Transfusion | Tagged , , , ,

Case 60 – the beginning

A 36 year old lady attends her antenatal booking appointment and has routine bloods taken including samples for blood grouping and antibody screen. Her Antibody panel and blood group screen is as follows: Please assume auto control negative and other … Continue reading

Posted in Paediatric haematology, Related to other specialities, Transfusion | Tagged , , ,

Case 31 part 4 – the beginning

Here’s the next installment in our series of short cases. This was a film from a nine year old post haematopoietic stem cell transplant for relapsed AML. The patient was one month post transplant with no evidence of AML but still … Continue reading

Posted in Anaemia, Laboratory morphology, Paediatric haematology, Platelet disorders, Transplant | Tagged , , | Leave a comment

Case 31 part 3 – summary

Some really helpful points from the team (#teamhaem on Twitter). This child presented to the emergency department with severe burns after an accident with boiling water. Phlebotomy was rather difficult, leading to rather poor sampling. Paediatric sampling can be difficult … Continue reading

Posted in Laboratory morphology, Paediatric haematology, Related to other specialities | Tagged , , | Leave a comment

Case 31 part 3 – update 1

Here’s the full blood count: Hb 110g/L MCV 82fL PLT 121×10*9/L WCC 11.9×10*9/L with neutrophilia The child is ill and has been brought in as an emergency. She is three years old and had a normal blood count a year … Continue reading

Posted in Anaemia, Paediatric haematology, Related to other specialities | Tagged | Leave a comment