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Category Archives: Platelet disorders
Case 100 (part D) – summary
The patient had mild thrombocytopenia and has suffered epistaxis. Epistaxis is relatively common and therefore structural causes should also be looked into. This is especially so if the nose bleeds are unilateral. There is a wide differential of why someone … Continue reading
Case 100 (part D) – update
You repeat the FBC and it shows similar results Hb 141g/l (130-180) MCV 89fl (82-98) WCC 7.5×109/l (4-11) Neutrophils 4.7×109/l (1.7-7.5) Lymphocytes 2.1×109/l (1.5-4.5) Platelets 70×109/l (150-450) Coagulation screen – normal U&E/LFT – normal Blood film: Questions What is the … Continue reading
Case 100 (part D) – the beginning
You are a GP evaluating a 12 year old boy with persistent nose bleeds. He otherwise feels well with no past medical history. He is on no medications. FBC shows: Hb 140g/l (130-180) MCV 90fl (82-98) WCC 8.5×109/l (4-11) Neutrophils … Continue reading
Case 86 – part C2
Thanks for your help with this short case. We examined this blood film of an unwell female: The most striking abnormality is red cell fragmentation. This can be seen in: AIHA/Evans’ syndrome DIC Pregnancy-associated (HELLP, pre-eclampsia, malignant hypertension, fatty liver of … Continue reading
Posted in Laboratory morphology, Platelet disorders, Thrombosis, Transfusion
Tagged FFP, haemolysis, plasma exchange, red cell fragmentation, thrombosis, TTP
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Case 81 – summary
Thank you for all the contributions to the case this week. The case We looked at a case of a 58 year gentleman who had an incidental finding of thrombocytopenia, whilst on apixaban therapy. Immediate intervention was required to stop … Continue reading
Posted in Acquired bleeding, Anticoagulation, Platelet disorders
Tagged anticoagulation, bleeding, ITP, thrombocytopenia
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Case 81 – update 2
Thankfully the bleeding resolves and no surgical intervention is required The platelet count responds to IVIG, and dexamethasone 40mg given for four days. Any further investigations required? 2 week s following commencement of steroids the platelet count has fallen … Continue reading
Posted in Acquired bleeding, Anticoagulation, Platelet disorders
Tagged anticoagulation, bleeding, ITP, thrombocytopenia
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Case 81 – update 1
Our followers have come up with a very comprehensive list of investigations! Our advice/investigation included stopping apixaban Checking Fbc ? Any other abnormalities/previous FBC/ clot in sample coagulation. Prolonged PT, normal aptt and fibrinogen renal and liver function HIV, hepatitis … Continue reading
Posted in Acquired bleeding, Anticoagulation, Platelet disorders
Tagged anticoagulation, bleeding, thrombocytopenia
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Case 81 – the beginning
A 58 year old gentlemen has routine bloods taken at the GP surgery. He is noted to have a platelet count of 38. His doctor rings you as the haematology registrar for advise as he is on apixaban for treatment … Continue reading
Posted in Acquired bleeding, Anticoagulation, Platelet disorders
Tagged anticoagulation, thrombocytopenia
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Case 61 – summary
Thank you for all your help this week! This week we looked at a case of childhood ITP. Our patient presented with easy bruising over a 3 week period, and had had a minor urti the previous month. The patient … Continue reading
Posted in Acquired bleeding, Platelet disorders
Tagged bleeding, easy bruising, iron deficiency, ITP, microcytosis, thrombocytopenia
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Case 61 – update 2
So time for another update! Our patient has been started on oral iron for a iron deficiency anaemia. Given that she only has some bruising and a slight petechial rash the decision has been made to monitor her, but not … Continue reading
Posted in Acquired bleeding, Platelet disorders
Tagged bleeding, easy bruising, iron deficiency, ITP, microcytosis, thrombocytopenia
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Case 61 – update 1
What have we found out so far? We have a 15 year old girl who has presented with a few week history of easy bruising. Blood tests have shows a microcytic anaemia with ferritin of 5 and a thrombocytopenia with … Continue reading
Posted in Acquired bleeding, Platelet disorders
Tagged bleeding, easy bruising, microcytosis, thrombocytopenia
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Case 61 – the beginning
Welcome to our new case!This week we start in a gp practice. A 15 year old girl has attended with her mum as she has had problems with easy bruising. She has no other pmh. What would you like to … Continue reading
Case 32 – summary
Our patient has now been on argatroban for 5 days and his plt count has risen to 115. He has no evidence of bleeding and no thrombosis. He continues to improve post operatively and is starting to mobilise. Given that … Continue reading
Case 32 – update 2
Our patient has been found to be HIT positive on the ELISA. He initially had a HIT screen test with a rapid gel agglutination assay for antibodies directed against the PF4/heparin complexes which is positive. This test has a good … Continue reading
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