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Category Archives: Platelet disorders
Case 31 part 4 – summary
Thanks for all of your comments. The film had numerous red cell changes including fragmentation (schistocytes), Howell Jolly bodies, accanthocytes, spherocytes. There was also thrombocytopenia and Howell-Jolly like inclusions in the neutrophils. The most significant finding are the red cell fragmentation. … Continue reading
Case 31 part 4 – the beginning
Here’s the next installment in our series of short cases. This was a film from a nine year old post haematopoietic stem cell transplant for relapsed AML. The patient was one month post transplant with no evidence of AML but still … Continue reading
Posted in Anaemia, Laboratory morphology, Paediatric haematology, Platelet disorders, Transplant
Tagged Blood film, haemolysis, MAHA
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Case 30 – summary
We have established that our newborn baby with an intracranial haemorrhage has a low platelet count and have debated the likely cause for this. The list of differentials include: Maternal ITP (Immune thrombocytopenic purpura: autoimmune destruction of platelets) which can … Continue reading
Posted in Paediatric haematology, Platelet disorders, Transfusion
Tagged NAIT, paediatrics, platelets, thrombocytopenia
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Case 30 – update 1
So, we have a neonate with an intracranial haemorrhage, diagnosed after birth due to decreased responsiveness. You had a number of questions for mum and suggestions for tests, including: HISTORY: Medications taken during pregnancy: only folic acid. Unexplained bleeding in … Continue reading
Posted in Paediatric haematology, Platelet disorders, Transfusion
Tagged paediatrics, thrombocytopenia
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Case 30 – the beginning
And we don’t mean we’ve only just entered our 4th decade (we wish!) but that we are now on to our 3oth case. So far we’ve covered a massive range of topics, from common conditions to the truly obscure, neonatal medicine … Continue reading
Posted in Paediatric haematology, Platelet disorders, Transfusion
Tagged paediatrics, thrombocytopenia
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Morphology week – summary
Slide 1 Answer: Bernard Soulier syndrome, bleeding disorder characterized by thrombocytopenia and large platelets. Autosomal recessive inheritance. Presentation consistent with low or dysfunctional platelets and include easy bruising, nosebleeds, mucosal bleeding, menorrhagia, and, occasionally, GI bleeding. Slide 2 Answer: Hairy cell leukaemia. … Continue reading
Morphology week – case 1
Spot diagnosis morphology for this week at teamhaem! New blood film/marrow uploaded each day. Please feel free to share any interesting blood films or marrows you have seen, and test our teamhaem followers! How would you report this blood film? … Continue reading