Category Archives: Transplant

Case 31 part 4 – summary

Thanks for all of your comments. The film had numerous red cell changes including fragmentation (schistocytes), Howell Jolly bodies, accanthocytes, spherocytes. There was also thrombocytopenia and Howell-Jolly like inclusions in the neutrophils. The most significant finding are the red cell fragmentation. … Continue reading

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Case 31 part 4 – the beginning

Here’s the next installment in our series of short cases. This was a film from a nine year old post haematopoietic stem cell transplant for relapsed AML. The patient was one month post transplant with no evidence of AML but still … Continue reading

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Case 20 – summary

Veno-occlusive disease Veno-occlusive disease is a post bone marrow transplant complication. A combination of pre-transplant risk factors, and transplant related conditions are believed to trigger primary hepatic sinusoidal injury, although a definitive underlying cause is unknown.  This can lead to … Continue reading

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Case 20 – update 3

looking at this case the aim was to identify potential post transplant complications.  Veno-occlusive hepatic disease is high on the list of differentials!  How would you diagnosis this? any other features on presentation?  possible treatments?

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Case 20 – update 2

Consider the differential diagnosis in this case! How would you investigate further? Would you initiate any treatment immediately?

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Case 20 – update 1

You review this lady on a daily basis.  Over the next few days you note the bilirubin starts to rise over the next few days. What other investigations would you wish to do? Differential diagnosis? Symptoms to help you determine … Continue reading

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Case 20 – the beginning

You review a 25 year old female on the haematology ward as part of the daily ward round. She is day +13 post allogeneic stem cell transplant for relapsed AML. What should you include in your assessment? Consider potential complications … Continue reading

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