Category Archives: Uncategorised

Case 107 – summary

Thank you for your contribution in this week’s #teamhaem case. This week we have been looking at Transient Leukaemia of Down Syndrome (TL-DS). Background Between 5%- 30% children with Down syndrome (DS) are born with Transient Leukaemia of Down syndrome … Continue reading

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Case 107 – update 3

CXR and ECHO show no significant abnormalities. Abdo USS confirms hepatosplenomegaly but no ascites. There are no skin rashes and his blood tests are stable. Blood film report: Polycythaemic film. Pleomorphic blasts with evidence of cytoplasmic blebbing. Manual blast count … Continue reading

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Case 107 – update 2

You think the baby has some dysmorphic features. You look at his blood film. You also check his conjugated bilirubin and request CXR, abdominal USS and ECHO. Questions: 1. What are the main features and why? 2. What factors might … Continue reading

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Case 107 – update 1

You meet the baby with his mother. He was a little floppy at birth and not feeding well with a low grade fever. He is on 2L oxygen but with no respiratory distress. He is visibly jaundiced. The mother is … Continue reading

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Case 107 – the beginning

Welcome to our new #TeamHaem case. You are the haematology registrar. You get a phone call from a junior doctor on the neonatal ward. They have a 2 day old baby boy with jaundice. The baby seems stable, though he … Continue reading

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Case 106 – Summary

Thank you all for your contributions this week.   We focused on a patient with a new diagnosis of primary immune thrombocytopenia (ITP), please refer to TeamHaem case 11 for a full summary of this condition.   In the wake … Continue reading

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Case 106 – update 2

Our patient is in haematology outpatient clinic. We have excluded any secondary causes for an isolated thrombocytopenia and are considering first line therapy with prednisolone 1mg/kg/day with gastric protection (our local #TeamHaem preference). We have considered the potential risks of … Continue reading

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Case 106 – update 1

You are checking the results from yesterday’s surgery and review our patients consultation notes: 61 year old female, previously fit and well ·        Easy bruising over both lower limbs for 2-3 weeks. No constitutional symptoms ·        No significant past medical history ·        No … Continue reading

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Case 106 – the beginning

Welcome to our new #TeamHaem case! You are working in a GP surgery. You see from your urgent surgery list that the next patient has registered with the practice within the last 24 hours and has told the receptionist she … Continue reading

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Case 105 update 2

Our patient was discussed at MDT and as many have suggested, he is treated with intensive chemotherapy. MATRIX – HD MTX, cytarabine, thiotepa and rituximab is the current regime recommended in the UK.  Intrathecal chemotherapy is not advocated in the BSH … Continue reading

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Case 105 update 1

MRI performed at the tertiary centre showed no evidence of a cerebral lesion.  You therefore plan with the neurosurgical team to stop the steroids and repeat the MRI after a short interval (2-4 weeks) whilst monitoring the patient closely.   … Continue reading

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Case 105

Welcome back! During your on call as the haematology registrar on the 2nd January you are contacted by the neurosurgical team.  A 54 year gentleman had been referred into the tertiary centre from a local hospital over the Christmas holidays.  … Continue reading

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CASE 105 – summary

Primary CNS lymphoma   1% of all non Hodgkin lymphomas, 3 % of all brain tumours.  It may [resent with a range of symptoms including focal motor deficits and behavioural change as seen in the patient in this case.   … Continue reading

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Christmas quiz

Thankyou for taking part in our Christmas quiz! Here are the questions and answers! 1. Which animals have: • Blue blood • Green blood • Yellow blood 2. The Japanese traditionally associate blood groups with personality. Can you match them … Continue reading

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TeamHaem saves Christmas 🎄- the summary

“A DOAC, dear sir, and some stockings to boot!” “Thank you dear doctor, now off I must shoot!” “Take it easy!” I called as he jumped up tall, “We’ll review you in clinic, here’s a helpline to call.   Please … Continue reading

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TeamHaem saves Christmas 🎄- Part 3

‘Has anything changed since this time last year? Any illnesses or weight loss? Tell me all, do not fear!’   Coyly he blushed as red as his suit ‘I’m afraid the answer is hidden by my boot’   Mrs Claus … Continue reading

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TeamHaem saves Christmas 🎄- Part 2

His eyes twinkled like stars, his sats 92, “You must let me home I have work to do!”   I have no time to lounge around here, Who is going to train and feed the reindeer?”   “Do you fly … Continue reading

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Team Haem saves Christmas 🎄 – Part 1

Twas the week before Christmas and all through the lab not an analyser was stirring, ten winks I did grab.   When then from my call phone there arose such a clatter, I sprang from my bench to see what … Continue reading

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Case 103 – summary

Thankyou for your help with this week’s case! Our patient has an intravascular transfusion reaction which was likely due anti C with undetectable antibodies. Red cell phenotyping of the patient and the transfused red cells help identify the likely antibody. … Continue reading

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Case 103 – update 2

We think our patient may have had an intravascular haemolytic transfusion reaction, although our negative investigations so far are unusual. The patient’s Hb is now around 55g/l. The creatinine is now around 500umol/l. Bilirubin is now 20 and haemoglobinuria resolves … Continue reading

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