Category Archives: Uncategorised

Case 124 – Update 2

Thank you for all of your input and suggestions. To summarise the case thus far: 68 year old lady referred with a macrocytic anaemia and thrombocytosis: Haemoglobin              87 g/L (115 – 165) White cell count          5.2 x 109/L … Continue reading

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Case 124 – Update 1

We are investigating a 68 year old lady referred with a macrocytic anaemia and thrombocytosis. Thanks for all of your helpful input thus far. Tests you have requested to date: Haemoglobin              87 g/L (115 – 165) White cell count … Continue reading

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Case 124 – The beginning

You are helping out in new patient haematology clinic. You have just had your post-lunch coffee and are raring to go! The next patient has been referred via the 2ww pathway by their GP for investigation of an abnormal FBC, … Continue reading

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case 123 summary

Our case this week looked at a 44 year old gentleman with a new diagnosis of AML. He presented with pancytopenia and blasts with auer rods on peripheral blood. Investigations confirmed a diagnosis of AML.  PML – RARA was negative, … Continue reading

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Case 123 update 2

The plan is to commence treatment with DA+myelotarg Cytogenetic and molecular studies show t(8:21) C-KIT positive FLT3 negative NPM1 negative Would this change your management? How are you going to monitor response in this patient?

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Case 123 update 1

 Our 44 year old male presented with the following full blood count Hb 62 WCC 35 plt 22 Blood film identified blasts, with auer rods. Blood film shows blasts cells, auer rods noted, thrombocytopenia and anaemia. Differential has included AML … Continue reading

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Case 123

44 year old man present to GP with fatigue, SOB and petechial rash. What investigations would you perform?  Level of urgency?? Please reply to us (@TeamHaem) on Twitter and always include #TeamHaem to allow others to follow your comments. Please … Continue reading

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Team Haem saves Christmas: The Summary

Jingle bells, jingle bells Jingle all the way Oh what fun it is to tweet TeamHaem’s case today!   The haemolysis is self-limiting No more parasites are seen The pitted red cells that have lost malaria Are being chomped up … Continue reading

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TeamHaem Saves Christmas Part 3

Jingle bells, jingle bells Jingle all the way Oh what fun it is to tweet TeamHaem’s case today!   Whilst sorting through the letters Poor Jingle remembers a bite A sneaky mosquito from an envelope Then that naughty insect took … Continue reading

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TeamHaem Saves Christmas Part 2

Jingle bells, jingle bells Jingle all the way Oh what fun it is to tweet TeamHaem’s case today!   Father Christmas is so worried Jingle sorts out both his lists He checks on who’s behaving And makes sure no-one’s missed. … Continue reading

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TeamHaem help us save Christmas 2019! 🎄❄️ Part 1

Jingle bells, jingle bells Jingle all the way Oh what fun it is to tweet TeamHaem’s case today!   A day or two ago  Father Christmas needed help Jingle, his top packing elf, Just wasn’t feeling himself   Jingle bells, jingle bells Jingle … Continue reading

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Case 121 – Summary!

This week we followed our patient with relapsed/refractory DLBCL through CAR T-cell therapy. We managed her cytokine release syndrome (CRS) and she is in remission thus far. CAR T-cell therapy Chimeric Antigen Receptor (CAR) T-cells are modified T cells in … Continue reading

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Case 121 – update 3!

We manage our patient with CAR T-cell therapy related CRS/ICANS with supportive care, including organ support from our critical care colleagues, and tocilizumab (anti-IL-6) therapy. She responds well to therapy and is stepped down to the haematology ward for ongoing … Continue reading

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Case 121 – Update 2!

We suspect cytokine-release syndrome (CRS) in our patient 5 days post CAR T-cell infusion. We manage her with aggressive fluid boluses, low-flow nasal cannula oxygen and paracetamol. We also complete a septic screen and cover her with broad-spectrum antibiotics. Her … Continue reading

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Case 121 – Update 1!

Our 48 year old patient with relapsed/refractory DLBCL is referred for consideration of CAR T-cell therapy. She is managed with IVE chemotherapy as a ‘bridging treatment’ and is subsequently admitted for CAR T-cell infusion. You are the on-call haematology SpR. … Continue reading

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Case 121 – The Beginning!

Welcome to another TeamHaem clinical case! Get involved and help shape the care of our fictional patient…… You review a 48 year old patient in lymphoma clinic. She was diagnosed with stage IVA diffuse large B cell lymphoma (DLBCL), with … Continue reading

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Case 120 – Summary!

Thank you for everyone’s contributions this week. We discussed the management of a 57 year old lady who was suffering a major haemorrhage secondary to a road traffic accident. The key points of managing a major haemorrhage (from haem perspective) … Continue reading

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Case 120 – Update 4!

Well done team – with your input I’m pleased to say she has now stabilised and has stopped bleeding!!! To achieve this she has been transfused: 8 units red blood cells 8 units FFP 1 pool of platelets 2 pools … Continue reading

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Case 120 – Update 3!

Thank you for everyone’s ongoing input. Our patient is more haemodynamically stable but continues to have ongoing bleeding. She is now receiving group specific/compatible blood products. She has currently received: 6 units packed red cells. 6 units FFP 1g tranexamic … Continue reading

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Case 120 – Update 2!

Thanks for everyone’s contributions so far! Our 57 year old female patient is haemorrhaging following a road traffic accident. The multidisciplinary team are trying to establish source control of the bleeding. The major haemorrhage protocol has been activated. She has … Continue reading

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