Tag Archives: Beta-thalassaemia

Case 49 – summary

Thanks to everyone who  tweeted for our case! The learning points are summarised below.   The case was based around a nulliparous 27 yr old women with sickle cell disease.  She wished to seek prior to conception.  Ideally pregnancy’s should … Continue reading

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Case 49 – update 2

The patient presents to a&e with shortness of breath at 22weeks gestation.   how would you assess this patient? management? differential?

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Case 49 – update 1

Partner testing reveals beta- thal trait.  How would you council this lady? The patient was commenced on hydroxycarbamide two years ago due to recurrent acute chest crisis.   As suggested by one of our followers – advice would be to … Continue reading

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Case 49 – the beginning

Our case this week focuses around a 27 year old lady who is know to have sickle cell disease.  She attends the joint haematology/obstetric clinic for preconceptual counselling.   As the junior haematology registrar in this clinic, consider how you … Continue reading

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Case 36 – update 2

Following testing of the father, he is also found to be a carrier of Beta-thalassaemia.  The pregnancy continues, and following counselling the family decline any further investigation until the fetus is born. What would be the options for testing prior … Continue reading

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Case 36 – update 1

Patients’ blood film looks like this: Ferritin level was also checked : 10 ug/l Family origin questionnaire has been mentioned and should be performed at all antenatal visits.  However all women – in both high prevalence and low prevalence areas … Continue reading

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Case 36 – the beginning

A 22 year old women has her antenatal booking in bloods taken. Her FBC shows Hb 10.2 g/dl MCV 71 fL (77-95fL) MCH 22 pg (26-33 pg) MCHC 33 g/dl (31-36g/dl) RDW 12.5% (11.5-14.5%) What features may be present on … Continue reading

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Morphology week – summary

Slide 1 Answer:  Bernard Soulier syndrome, bleeding disorder characterized by thrombocytopenia and large platelets.  Autosomal recessive inheritance.  Presentation consistent with low or dysfunctional platelets and include easy bruising, nosebleeds, mucosal bleeding, menorrhagia, and, occasionally, GI bleeding. Slide 2 Answer:  Hairy cell leukaemia. … Continue reading

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