Tag Archives: coagulation

Case 37 part 2 – the beginning

The APTT can be rather sneaky at times! In part one of this case we saw how the APTT can be prolonged in factor deficiencies. You are working in a small hospital and the surgical team request fresh frozen plasma for … Continue reading

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Case 37 part 1 – update 2

Our patient who is pre-op has had a routine coagulation screen has a prolonged APTT which corrects on mixing with normal plasma, indicating a possible coagulation factor deficiency. If the APTT does not correct it would suggest an antibody interfering … Continue reading

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Case 37 part 1 – update 1

The history is frequently forgotten when worrying about coagulation tests and it is the most important factor. The patient was contacted the next day and he confirms that he has no bleeding problems and is on no medications.  He has … Continue reading

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Case 37 part 1 – the beginning

This week we’re going to present a series of short cases around clotting results. Hopefully we’ll demonstrate when coagulation screens should be used and also how to interpret basic abnormalities. It most be noted that different labs will use different … Continue reading

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Case 35 – summary

Thank you for all of your comments this week! This week we took a walk through acquired factor VIII inhibitors. Acquired haemophilia A is a rare disorder with an incidence of around 1.5 per 1 million per year. There can … Continue reading

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Case 35 – update 2

We have diagnosed our patient with acquired haemophilia A. They have also had a CT scan which is highly suspicious of a caecal cancer. Given the acquired haemophilia it was felt unsafe to proceed with invasive investigations for the caecal … Continue reading

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Case 35 – update 1

What have we found out so far? We have a 67 year old gentleman who has presented with a 2 day history of thigh pain and swelling. An u/s has shown an intramuscular haematoma. He was on warfarin for AF … Continue reading

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Case 35 – the beginning

Welcome to our new case that we will see develop over the next week with your help! A 67 year old gentleman presents to his gp with a 2 day history of pain and swelling in his right thigh.  On … Continue reading

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Case 6 – summary

Beriplex use for warfarin reversal Using the BCSH guidelines, we can identify that this patient requires reversal of warfarin immediately, given the history of a possible fall (head injury) and the history of amnesia. Major bleeding is defined as limb … Continue reading

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Case 6 – update 2

So …. CT confirms a subdural bleed and the patient has recieved beriplex at a dose of 30 units/kg and vitamin K 2mg IV.  Initial INR was 2.6 and repeat INR 30mins following beriplex was 1.2.    Discussion with neurosurgeons … Continue reading

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Case 6 – update 1

20 minutes after his son reports that he appears more confused.  On review you note a slight facial droop, his speech is a little slurred, and he is definitely more confused.  His daughter has brought in a list of medications … Continue reading

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Case 6 – the beginning

You are working a night shift in A&E.  A 82 year old gentleman attends with his son.  The son reports that his father had a fall earlier that day.  The son was in the house, but did not witness the fall.  … Continue reading

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