Tag Archives: Delayed transfusion reaction

Case 90 – summary

We started with a 74 year old gentleman who was admitted with weight loss, fatigue and change in bowel habit. A mass in the right iliac fossa was palpated and a colonic malignancy was suspected. He had thrombocytosis with microcytic indices … Continue reading

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Case 90 – update 4

Here is the antibody panel. Can you identify the antibody?  

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Case 90 – update 3

Our patient is one week post two units of blood and his haemoglobin is back to baseline and has hyperbilirubinaemia. LDH is elevated and haptoglobins are absent. Blood film shows spherocytes. Here is the antibody screen Questions (For fun!) can … Continue reading

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Case 90 – update 2

Our patient is treated for potential pulmonary oedema associated with blood transfusion (transfusion-associated circulatory overload). The differential was TRALI but given its rarity and the patient’s observations (hypertension and a positive fluid balance) TACO was felt to be more likely. … Continue reading

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Case 34 – summary

This was a varied case centered around an unwell patient with sickle cell anaemia post surgery. There were a number of themes to cover in this case reminding us that patients with sickle cell anaemia can be complex and require … Continue reading

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Case 19 – summary

There are a number of important points to this case. 1) The patient is known to be chronically neutropenic because of myelodysplasia.  Myelodysplasia results in varying degrees of pancytopenia due to a clonal bone marrow malignancy.  Patients are at risk … Continue reading

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Case 19 – update 6

For the start of the case scroll below… or click https://teamhaem.wordpress.com/2014/01/26/case-19-the-beginning/ The team have correctly identified that the patient is having a delayed transfusion reaction.  The fevers she complained of initially may have been due to this but concurrent infection may … Continue reading

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Case 19 – update 5

For the start of the case scroll below… or click https://teamhaem.wordpress.com/2014/01/26/case-19-the-beginning/ So far our patient with chronic neutropenia due to myelodysplasia has been admitted with fevers and anaemia.  She only had a transfusion a matter of days ago, so her anaemia … Continue reading

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