Tag Archives: dysplasia

Case 96 – summary

Thank you for participating in our case this week. This week we have been looking at a case of JMML (Juvenile myelomonocytic leukaemia), which is a rare clonal haematopoietic disorder of childhood, characterised by the proliferation of granulocytic and monocytic … Continue reading

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Case 96 – update 4

The haematology team has now taken over his care. Bone marrow aspirate has demonstrated a hypercellular marrow with left shift, and there are increased myeloid and monocyte lineages. Blast count is about 4%. There is occasional evidence of haemophagocytosis and … Continue reading

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Case 96 – update 3

The blood film has been reported: – leukocytosis with neutrophilia and monocytosis, there is left shift and toxic granulation and vacuolation. Occasional primitive cells ~ 2%. No nucleated RBCs. The appearances might be reactive/infection related, and infection as well as … Continue reading

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Case 96 – update 2

An USS abdomen has been performed which confirms mild hepato-splenomegaly. CXR was reported as normal. Faecal elastase, TTG, TFTs, ILGF1 all normal. You phone the haematology registrar to look at the blood film in view of the abnormal FBC. Questions: … Continue reading

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Case 77 – summary

Case 77 Summary   Thanks to everyone who contributed to the case this week.   Our case started with a blood film to test our morphology skills.Β  We picked up that the blood film showed: Dysplastic neutrophils Blasts NRBCs Tear … Continue reading

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Case 77 – update 2

Bone marrow results: 13% blasts evidence of dysplasia in the erythroid and myeloid cell lines Cytogenetics:trisomy 8   How would you classify this patient? What would be your approach to management?

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Case 77 – update 1

So far, we have a 54 year old male who is pancytopenic. Β He demonstrates features of myelodysplasia on blood film. we have not had any clinical details, but most have suggested admission which does not seem unreasonable given the patients … Continue reading

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