Tag Archives: haemolytic anaemia

Case 72- summary

Answers A – hereditary elliptocytosis B – hairy cell leukaemia C – metastatic prostate cancer Case A The first case, we started with something relatively straightforward: This was a blood film of a 21 year old pregnant women who was … Continue reading

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Case 72 – case A

Evening. This week we are going to do some short cases based around morphology.  The aim is for this to be a quick fire week, with lots of interesting pictures!  We would welcome any contribution from our followers too – so tweet in a picture … Continue reading

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Case 34 – summary

This was a varied case centered around an unwell patient with sickle cell anaemia post surgery. There were a number of themes to cover in this case reminding us that patients with sickle cell anaemia can be complex and require … Continue reading

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Case 34 – update 4

Our patient with sickle cell anaemia has been investigated for a delayed haemolytic transfusion reaction. However, the reticulocyte count was not elevated and the direct antiglobulin test was not positive as would be expected. Similarly there was no new antibody … Continue reading

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Case 34 – update 3

Lots of great suggestions via #teamhaem. Patients with sickling disorders need careful attention when operations are being planned. They should be carefully pre-assesed with involvement of haematologists and anaesthetists.  Important points include: Respiratory function post op – high risk of … Continue reading

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Case 34 – update 2

We have a patient with sickle cell anaemia post op who is now more anaemic. She also has a sickle cell crisis with abdominal pain. She has a rather elevated CRP which may be post op or due to the … Continue reading

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Case 34 – update 1

Thanks for all of the great contributions on Twitter via #teamhaem We have initiated basic treatment for patients with a potential sickle cell crisis: Oxygen if hypoxic Hydration Analgesia Keep warm Low threshold for antibiotics Septic screen Our patients investigations show: … Continue reading

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Case 17 – update 2

So the team are worried about haemolytic anaemia.  The blood film is made. Questions: What does the film show? Does this help us out? Please reply on Twitter and always include #teamhaem to allow others to follow your comments. Please … Continue reading

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Case 17 – update 1

Excellent work on this week’s case.  Almost all of the causes of macrocytosis have been identified: B12/folate deficiency Reticulocytosis Liver disease Alcohol excess Myelodysplastic syndromes Paraproteinaemia Hypothyroidism Pregnancy Cold agglutinins Drugs – DMARDS, chemotherapy, folate antagonists e.g. methotrexate, sulfasalizine, hydrocycarbamide, … Continue reading

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Case 8 – summary

Summary of case 8 – PNH This case demonstrated presenting symptoms of haemolytic anaemia.  This was indicated by a low HB, raised LDH, raised reticulocytes, elevated bilirubin, and low haptoglobin levels.  A negative DAT suggests that this is not an … Continue reading

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