Tag Archives: Lymphoma

Case 88 – part E

Last slide of the week. Spot diagnosis – patient presented with a vasculitis

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Case 69 – part 3 – summary

During this short case we looked at serum protein electrophoresis. This showed a band in the gamma region and immunofixation confirmed a IgM kappa paraprotein. IgM paraproteins are commonly associated with MGUS, low grade lymphoma and rarely myeloma. Typically IgM … Continue reading

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Case 69 – part 3 – the beginning

Thanks for contributing! Please use #TeamHaem in your reply on Twitter!   A 69 year old gentleman presents to his GP with headache and visual blurring. Giant cell arteritis is suspected as the ESR is 120mm/hr. A serum protein electrophoresis … Continue reading

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Case 65 – summary

Our case concentrated on presentation, investigation and management of DLBCL.   Case summary This 42 year old gentleman had presented with a history of B-symptoms and palpable lymphadenopathy.  Bloods tests revealed an acute kidney injury highlighting the need for urgent … Continue reading

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Case 56 – Summary

This weeks case dealt with the presentation of a rare lymphoma. James was found to have an NK cell lymphoma of the sinuses with a single cervical lymph node. He had an IPI score of 0 and no other co-morbidity. … Continue reading

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Case 56 – update 3

IPI score is calculated as 0 and there is evidence this may be prognostic to some extent in NK lymphomas. The MDT had no trials available so felt SMILE (Dexamethasone, methotrexate, Ifosfamide, L-Asparaginase and Etoposide) chemotherapy was a suitable option, … Continue reading

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Case 56 – update 2

The biopsy shows an angiocentric distribution of atypical lymphoid cells penetrating the blood vessel walls.The immunophenotype shows CD2 +, Surface CD 3 -, Cytoplasmic CD3 + and CD 56 + cells. James’ biopsy confirms a diagnosis of Nasal NK/T cell … Continue reading

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Case 56 – update 1

So far we have found out James has not been abroad, he is a lifelong non-smoker and has had no previous procedures. He has no past medical history and has no regular medications. Tests: Wcc 13, Hb 130, plt 260, … Continue reading

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Case 56 – the beginning

James a 48 year old painter presents to his GP with facial pain over his right cheek and a blocked nose with rhinorrhoea. James is given antibiotics for probable sinusitis. Three weeks later his symptoms are worse; he has constant … Continue reading

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Case 42 – summary

Thank you for all of your input! This time we looked at primary CNS lymphoma in an immunocompetent patient. Following 4 cycles of treatment with high dose methotrexate and cytarabine our patient had an excellent response on MRI. He went … Continue reading

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Case 42 – update 2

Our patient was admitted under the medical team following development of left arm weakness, in addition to his left leg weakness. A ct head with contrast has shown an enhancing frontal lesion, with perilesional oedema. An urgent neurosurgical opinion is … Continue reading

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case 42 – update 1

So we have a 47 year old gentleman. No past medical history. Works in telesales. He drinks 70 units of alcohol a week, for the last year. Doesn’t have a great diet, only occasionally eats vegetables. Lives alone, sees his … Continue reading

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Case 42 – the beginning

Welcome to our new case! This week we start in a gp surgery. A 47 year old gentleman attends because he has been having some problems with his memory, he has also noticed that he has been slightly unsteady on … Continue reading

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Case 38 – summary

Thank you for all your input this week!This case looked at a 32 year old gentleman who was diagnosed with burkitt lymphoma (BL) following a 3 week history of sweats, weight loss and an increasing abdominal mass and splenomegally. He … Continue reading

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Case 38 – update 2 

We have some more results. Ct scan shows 19cm splenomegally. There is a large lymph node mass in the left iliac fossa measuring 11×12 cm, there is also other widespread large volume abdominal lymphadenopathy. There are a few 1cm groin … Continue reading

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Case 38 – update 1

So what have we found out? We have a 32 year old male patient who has come back from a 2 year ’round the world’ trip 4/52 ago. He has travelled to Russia, China, India, Argentina, Kenya, Tanzania, Australia, Thailand … Continue reading

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Case 38 – the beginning

Welcome to our new case! Get involved as we see it evolve over the next week with your help. A 32 year old gentleman presents to a&e with a 3 week history of being generally unwell, fever, sweats and abdominal … Continue reading

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Case 9 – summary

Our patient had very non-specific symptoms and signs at the start, but as these persisted an X ray was performed which showed a mediastinal mass.  Differential diagnoses included thymoma, non-Hodgkin’s lymphoma, Hodgkin’s lymphoma, teratoma, benign tumour.  A concern was superior vena caval obstruction … Continue reading

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