Tag Archives: Lymphoma

Case 95 – summary

Thankyou for all your help this week. This week we had a look at mantle cell lymphoma (MCL). MCL is a type of none Hodgkin’s lymphoma, and comprises between 3 and 10% of NHL, and often has features of both … Continue reading

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Case 95 – update 2

We have monitored our patient for a year. Unfortunately at his most recent appointment he has begun to complain of weight loss of 7kg, drenching night sweats and fatigue. What would you want to do next? Are there any investigations … Continue reading

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Case 88 – part E

Last slide of the week. Spot diagnosis – patient presented with a vasculitis

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Case 69 – part 3 – summary

During this short case we looked at serum protein electrophoresis. This showed a band in the gamma region and immunofixation confirmed a IgM kappa paraprotein. IgM paraproteins are commonly associated with MGUS, low grade lymphoma and rarely myeloma. Typically IgM … Continue reading

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Case 69 – part 3 – the beginning

Thanks for contributing! Please use #TeamHaem in your reply on Twitter!   A 69 year old gentleman presents to his GP with headache and visual blurring. Giant cell arteritis is suspected as the ESR is 120mm/hr. A serum protein electrophoresis … Continue reading

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Case 65 – summary

Our case concentrated on presentation, investigation and management of DLBCL.   Case summary This 42 year old gentleman had presented with a history of B-symptoms and palpable lymphadenopathy.  Bloods tests revealed an acute kidney injury highlighting the need for urgent … Continue reading

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Case 56 – Summary

This weeks case dealt with the presentation of a rare lymphoma. James was found to have an NK cell lymphoma of the sinuses with a single cervical lymph node. He had an IPI score of 0 and no other co-morbidity. … Continue reading

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Case 56 – update 3

IPI score is calculated as 0 and there is evidence this may be prognostic to some extent in NK lymphomas. The MDT had no trials available so felt SMILE (Dexamethasone, methotrexate, Ifosfamide, L-Asparaginase and Etoposide) chemotherapy was a suitable option, … Continue reading

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Case 56 – update 2

The biopsy shows an angiocentric distribution of atypical lymphoid cells penetrating the blood vessel walls.The immunophenotype shows CD2 +, Surface CD 3 -, Cytoplasmic CD3 + and CD 56 + cells. James’ biopsy confirms a diagnosis of Nasal NK/T cell … Continue reading

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Case 56 – update 1

So far we have found out James has not been abroad, he is a lifelong non-smoker and has had no previous procedures. He has no past medical history and has no regular medications. Tests: Wcc 13, Hb 130, plt 260, … Continue reading

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Case 56 – the beginning

James a 48 year old painter presents to his GP with facial pain over his right cheek and a blocked nose with rhinorrhoea. James is given antibiotics for probable sinusitis. Three weeks later his symptoms are worse; he has constant … Continue reading

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Case 42 – summary

Thank you for all of your input! This time we looked at primary CNS lymphoma in an immunocompetent patient. Following 4 cycles of treatment with high dose methotrexate and cytarabine our patient had an excellent response on MRI. He went … Continue reading

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Case 42 – update 2

Our patient was admitted under the medical team following development of left arm weakness, in addition to his left leg weakness. A ct head with contrast has shown an enhancing frontal lesion, with perilesional oedema. An urgent neurosurgical opinion is … Continue reading

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case 42 – update 1

So we have a 47 year old gentleman. No past medical history. Works in telesales. He drinks 70 units of alcohol a week, for the last year. Doesn’t have a great diet, only occasionally eats vegetables. Lives alone, sees his … Continue reading

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Case 42 – the beginning

Welcome to our new case! This week we start in a gp surgery. A 47 year old gentleman attends because he has been having some problems with his memory, he has also noticed that he has been slightly unsteady on … Continue reading

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Case 38 – summary

Thank you for all your input this week!This case looked at a 32 year old gentleman who was diagnosed with burkitt lymphoma (BL) following a 3 week history of sweats, weight loss and an increasing abdominal mass and splenomegally. He … Continue reading

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Case 38 – update 2 

We have some more results. Ct scan shows 19cm splenomegally. There is a large lymph node mass in the left iliac fossa measuring 11×12 cm, there is also other widespread large volume abdominal lymphadenopathy. There are a few 1cm groin … Continue reading

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Case 38 – update 1

So what have we found out? We have a 32 year old male patient who has come back from a 2 year ’round the world’ trip 4/52 ago. He has travelled to Russia, China, India, Argentina, Kenya, Tanzania, Australia, Thailand … Continue reading

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Case 38 – the beginning

Welcome to our new case! Get involved as we see it evolve over the next week with your help. A 32 year old gentleman presents to a&e with a 3 week history of being generally unwell, fever, sweats and abdominal … Continue reading

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Case 9 – summary

Our patient had very non-specific symptoms and signs at the start, but as these persisted an X ray was performed which showed a mediastinal mass.  Differential diagnoses included thymoma, non-Hodgkin’s lymphoma, Hodgkin’s lymphoma, teratoma, benign tumour.  A concern was superior vena caval obstruction … Continue reading

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