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Tag Archives: Lymphoma
Case 88 – part E
Last slide of the week. Spot diagnosis – patient presented with a vasculitis
Posted in Chronic leukaemia, Laboratory morphology, Lymphoma
Tagged cryoglobulinaemia, Lymphoma, morphology, vasculitis
Case 69 – part 3 – summary
During this short case we looked at serum protein electrophoresis. This showed a band in the gamma region and immunofixation confirmed a IgM kappa paraprotein. IgM paraproteins are commonly associated with MGUS, low grade lymphoma and rarely myeloma. Typically IgM … Continue reading
Posted in Lymphoma
Tagged electrophoresis, hyperviscosity, IgM paraprotein, Lymphoma, lymphoplasmacytic lymphoma, myeloma, Paraprotein, Waldrenstroms
Case 69 – part 3 – the beginning
Thanks for contributing! Please use #TeamHaem in your reply on Twitter! A 69 year old gentleman presents to his GP with headache and visual blurring. Giant cell arteritis is suspected as the ESR is 120mm/hr. A serum protein electrophoresis … Continue reading
Posted in Lymphoma
Tagged electrophoresis, hyperviscosity, IgM paraprotein, Lymphoma, lymphoplasmacytic lymphoma, myeloma, Paraprotein, Waldrenstroms
Case 65 – summary
Our case concentrated on presentation, investigation and management of DLBCL. Case summary This 42 year old gentleman had presented with a history of B-symptoms and palpable lymphadenopathy. Bloods tests revealed an acute kidney injury highlighting the need for urgent … Continue reading
Case 56 – Summary
This weeks case dealt with the presentation of a rare lymphoma. James was found to have an NK cell lymphoma of the sinuses with a single cervical lymph node. He had an IPI score of 0 and no other co-morbidity. … Continue reading
Posted in Lymphoma
Tagged chemotherapy, Extranodal lymphoma, Lymphoma, T cell lymphoma
Case 56 – update 3
IPI score is calculated as 0 and there is evidence this may be prognostic to some extent in NK lymphomas. The MDT had no trials available so felt SMILE (Dexamethasone, methotrexate, Ifosfamide, L-Asparaginase and Etoposide) chemotherapy was a suitable option, … Continue reading
Posted in Lymphoma
Tagged chemotherapy, Extranodal lymphoma, Lymphoma, T cell lymphoma
Case 56 – update 2
The biopsy shows an angiocentric distribution of atypical lymphoid cells penetrating the blood vessel walls.The immunophenotype shows CD2 +, Surface CD 3 -, Cytoplasmic CD3 + and CD 56 + cells. James’ biopsy confirms a diagnosis of Nasal NK/T cell … Continue reading
Posted in Lymphoma
Tagged chemotherapy, Extranodal lymphoma, Lymphoma, T cell lymphoma
Case 56 – update 1
So far we have found out James has not been abroad, he is a lifelong non-smoker and has had no previous procedures. He has no past medical history and has no regular medications. Tests: Wcc 13, Hb 130, plt 260, … Continue reading
Case 56 – the beginning
James a 48 year old painter presents to his GP with facial pain over his right cheek and a blocked nose with rhinorrhoea. James is given antibiotics for probable sinusitis. Three weeks later his symptoms are worse; he has constant … Continue reading
Posted in Lymphoma
Tagged chemotherapy, Extranodal lymphoma, Lymphoma, T cell lymphoma
Case 42 – summary
Thank you for all of your input! This time we looked at primary CNS lymphoma in an immunocompetent patient. Following 4 cycles of treatment with high dose methotrexate and cytarabine our patient had an excellent response on MRI. He went … Continue reading
Posted in Lymphoma
Tagged folate, Lymphoma, Neurology, primary CNS lymphoma, radiology
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Case 42 – update 2
Our patient was admitted under the medical team following development of left arm weakness, in addition to his left leg weakness. A ct head with contrast has shown an enhancing frontal lesion, with perilesional oedema. An urgent neurosurgical opinion is … Continue reading
Posted in Lymphoma
Tagged folate, Lymphoma, Neurology, primary CNS lymphoma, radiology
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case 42 – update 1
So we have a 47 year old gentleman. No past medical history. Works in telesales. He drinks 70 units of alcohol a week, for the last year. Doesn’t have a great diet, only occasionally eats vegetables. Lives alone, sees his … Continue reading
Posted in Lymphoma
Tagged folate, Lymphoma, Neurology, primary CNS lymphoma, radiology
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Case 42 – the beginning
Welcome to our new case! This week we start in a gp surgery. A 47 year old gentleman attends because he has been having some problems with his memory, he has also noticed that he has been slightly unsteady on … Continue reading
Posted in Lymphoma
Tagged folate, Lymphoma, Neurology, primary CNS lymphoma, radiology
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Case 38 – the beginning
Welcome to our new case! Get involved as we see it evolve over the next week with your help. A 32 year old gentleman presents to a&e with a 3 week history of being generally unwell, fever, sweats and abdominal … Continue reading
Case 9 – summary
Our patient had very non-specific symptoms and signs at the start, but as these persisted an X ray was performed which showed a mediastinal mass. Differential diagnoses included thymoma, non-Hodgkin’s lymphoma, Hodgkin’s lymphoma, teratoma, benign tumour. A concern was superior vena caval obstruction … Continue reading
Posted in Lymphoma
Tagged Lymphoma, PMBCL, Primary mediastinal B-cell lymphoma, SVCO
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