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Tag Archives: Lymphoma
Case 95 – summary
Thankyou for all your help this week. This week we had a look at mantle cell lymphoma (MCL). MCL is a type of none Hodgkin’s lymphoma, and comprises between 3 and 10% of NHL, and often has features of both … Continue reading
Posted in Chronic leukaemia, Laboratory morphology, Lymphoma
Tagged Lymphocytosis, Lymphoma, mantle cell lymphoma
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Case 95 – update 2
We have monitored our patient for a year. Unfortunately at his most recent appointment he has begun to complain of weight loss of 7kg, drenching night sweats and fatigue. What would you want to do next? Are there any investigations … Continue reading
Posted in Chronic leukaemia, Lymphoma
Tagged Lymphocytosis, Lymphoma, mantle cell lymphoma
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Case 88 – part E
Last slide of the week. Spot diagnosis – patient presented with a vasculitis
Posted in Chronic leukaemia, Laboratory morphology, Lymphoma
Tagged cryoglobulinaemia, Lymphoma, morphology, vasculitis
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Case 69 – part 3 – summary
During this short case we looked at serum protein electrophoresis. This showed a band in the gamma region and immunofixation confirmed a IgM kappa paraprotein. IgM paraproteins are commonly associated with MGUS, low grade lymphoma and rarely myeloma. Typically IgM … Continue reading
Posted in Lymphoma
Tagged electrophoresis, hyperviscosity, IgM paraprotein, Lymphoma, lymphoplasmacytic lymphoma, myeloma, Paraprotein, Waldrenstroms
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Case 69 – part 3 – the beginning
Thanks for contributing! Please use #TeamHaem in your reply on Twitter! A 69 year old gentleman presents to his GP with headache and visual blurring. Giant cell arteritis is suspected as the ESR is 120mm/hr. A serum protein electrophoresis … Continue reading
Posted in Lymphoma
Tagged electrophoresis, hyperviscosity, IgM paraprotein, Lymphoma, lymphoplasmacytic lymphoma, myeloma, Paraprotein, Waldrenstroms
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Case 65 – summary
Our case concentrated on presentation, investigation and management of DLBCL. Case summary This 42 year old gentleman had presented with a history of B-symptoms and palpable lymphadenopathy. Bloods tests revealed an acute kidney injury highlighting the need for urgent … Continue reading
Case 56 – Summary
This weeks case dealt with the presentation of a rare lymphoma. James was found to have an NK cell lymphoma of the sinuses with a single cervical lymph node. He had an IPI score of 0 and no other co-morbidity. … Continue reading
Posted in Lymphoma
Tagged chemotherapy, Extranodal lymphoma, Lymphoma, T cell lymphoma
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Case 56 – update 3
IPI score is calculated as 0 and there is evidence this may be prognostic to some extent in NK lymphomas. The MDT had no trials available so felt SMILE (Dexamethasone, methotrexate, Ifosfamide, L-Asparaginase and Etoposide) chemotherapy was a suitable option, … Continue reading
Posted in Lymphoma
Tagged chemotherapy, Extranodal lymphoma, Lymphoma, T cell lymphoma
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Case 56 – update 2
The biopsy shows an angiocentric distribution of atypical lymphoid cells penetrating the blood vessel walls.The immunophenotype shows CD2 +, Surface CD 3 -, Cytoplasmic CD3 + and CD 56 + cells. James’ biopsy confirms a diagnosis of Nasal NK/T cell … Continue reading
Posted in Lymphoma
Tagged chemotherapy, Extranodal lymphoma, Lymphoma, T cell lymphoma
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Case 56 – update 1
So far we have found out James has not been abroad, he is a lifelong non-smoker and has had no previous procedures. He has no past medical history and has no regular medications. Tests: Wcc 13, Hb 130, plt 260, … Continue reading
Case 56 – the beginning
James a 48 year old painter presents to his GP with facial pain over his right cheek and a blocked nose with rhinorrhoea. James is given antibiotics for probable sinusitis. Three weeks later his symptoms are worse; he has constant … Continue reading
Posted in Lymphoma
Tagged chemotherapy, Extranodal lymphoma, Lymphoma, T cell lymphoma
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Case 42 – summary
Thank you for all of your input! This time we looked at primary CNS lymphoma in an immunocompetent patient. Following 4 cycles of treatment with high dose methotrexate and cytarabine our patient had an excellent response on MRI. He went … Continue reading
Posted in Lymphoma
Tagged folate, Lymphoma, Neurology, primary CNS lymphoma, radiology
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Case 42 – update 2
Our patient was admitted under the medical team following development of left arm weakness, in addition to his left leg weakness. A ct head with contrast has shown an enhancing frontal lesion, with perilesional oedema. An urgent neurosurgical opinion is … Continue reading
Posted in Lymphoma
Tagged folate, Lymphoma, Neurology, primary CNS lymphoma, radiology
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case 42 – update 1
So we have a 47 year old gentleman. No past medical history. Works in telesales. He drinks 70 units of alcohol a week, for the last year. Doesn’t have a great diet, only occasionally eats vegetables. Lives alone, sees his … Continue reading
Posted in Lymphoma
Tagged folate, Lymphoma, Neurology, primary CNS lymphoma, radiology
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Case 42 – the beginning
Welcome to our new case! This week we start in a gp surgery. A 47 year old gentleman attends because he has been having some problems with his memory, he has also noticed that he has been slightly unsteady on … Continue reading
Posted in Lymphoma
Tagged folate, Lymphoma, Neurology, primary CNS lymphoma, radiology
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