Categories
Search
Follow me on Twitter
My Tweets-
Recent Posts
Tag Archives: morphology
Case 100 (part D) – summary
The patient had mild thrombocytopenia and has suffered epistaxis. Epistaxis is relatively common and therefore structural causes should also be looked into. This is especially so if the nose bleeds are unilateral. There is a wide differential of why someone … Continue reading
Case 100 (part D) – update
You repeat the FBC and it shows similar results Hb 141g/l (130-180) MCV 89fl (82-98) WCC 7.5×109/l (4-11) Neutrophils 4.7×109/l (1.7-7.5) Lymphocytes 2.1×109/l (1.5-4.5) Platelets 70×109/l (150-450) Coagulation screen – normal U&E/LFT – normal Blood film: Questions What is the … Continue reading
Case 100 (part C) – update 1
Our patient has a mildly elevated lymphocyte count and this is persistent on repeat. In the absence of reactive causes the most likely explanation is a low grade lymphoproliferative neoplasm such as CLL. After a period of monitoring the patient’s … Continue reading
Case 99 – update 3
A bone marrow biopsy has been carried out: (see below) Aspirate shows erythroid hypoplasia but no dysplastic features. Cellularity is normal and megakaryocyte & granulocyte lineages are normal. For interest, also see Trephine IHC with Glycophorin-C staining – demonstrating reduced … Continue reading
Posted in Anaemia, Laboratory morphology, Paediatric haematology
Tagged anaemia, blood transfusion, Bone marrow, morphology, paediatrics
Leave a comment
Case 88 – summary
Morphology week summary. Case A Our followers were correct in suggesting these were plasma cells, one of which is binucleate on the second picture. Thrombocytopenia was also noted. This would be in keeping with a diagnosis of plasma … Continue reading
Case 88 – part E
Last slide of the week. Spot diagnosis – patient presented with a vasculitis
Posted in Chronic leukaemia, Laboratory morphology, Lymphoma
Tagged cryoglobulinaemia, Lymphoma, morphology, vasculitis
Leave a comment
Case 88 – parts C and D: update
Flow cytometry results. Not true to life I know but just for a bit of fun and test our morphology and flow skills….. The following results are for our two patients- what is the diagnosis for each? Which results goes … Continue reading
Case 88 – parts C and D
You are reviewing the blood film tray and a further two patients are noted to have lymphocytosis Case C Hb 96 g/L WCC 34 (10^9/L) Case D Hb 100 g/L WBC 23 (10^9/L) Can you describe the findings? Do they … Continue reading
Case 88 – part B: update
As requested by some followers Flow cytometry : CD5 + CD23 – SmIg strong FMC7 ++ CD20 ++ CD22 ++ CD19+ CD79b ++ CD200 ++ CD10- Cyclin D1 expression (11:14)(q13:32)negative Splenomegaly noted on examination, with no evidence of lymphadenopathy. … Continue reading
Case 88 – part B
84 year old man Hb 111 WBC 24 Describe the findings on the blood film What further clinical information would you wish to know? further investigations?
Case 88 – part A
This week we are going to do some quick fire morphology cases. Cases will be centered around a blood film, then added questions based on the diagnosis our followers come up with. Please feel free to add interesting pictures of … Continue reading
Posted in Laboratory morphology, Myeloma/paraproteins
Tagged morphology, myeloma, Plasma cell leukaemia
Leave a comment
Case 86 – part A2
This short case focused on the diagnosis of thalassaemia over iron deficiency. The below factors can help, but there are many overlapping factors and this is more of a guide rather than absolute. Factors that may make this unreliable include … Continue reading
Posted in Anaemia, Haemoglobinopathy, Laboratory morphology
Tagged anaemia, Blood film, haemoglobinopathy, HbEE, HPLC, microcytosis, morphology, thalassaemia
Leave a comment
Case 86 – part A1
Welcome to #TeamHaem. This week we are going to look at some blood film morphology. A 21 year old female student has a full blood count done due to fatigue. Hb 100g/L MCV 74fl MCH 21.7pg Platelets 250×109/l WCC and … Continue reading
Posted in Anaemia, Haemoglobinopathy, Laboratory morphology
Tagged anaemia, Blood film, haemoglobinopathy, HbEE, HPLC, microcytosis, morphology, thalassaemia
Leave a comment
TeamHaem 