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Tag Archives: Paraprotein
Case 91 – summary
Thank you for all your contributions this week! This week we had a look at MGUS (monoclonal gammopathy of undetermined significance). Our patient was diagnosed with IgA lambda MGUS, which was monitored 6 monthly for 4 years. This then progresses … Continue reading
Posted in Myeloma/paraproteins
Tagged MGUS, monoclonal gammopathy, myeloma, Paraprotein
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Case 91 – update 2
We have been monitoring our patient 6 monthly for 4 years. His para protein has been slowly rising and was 10g/l on his last visit 3 months ago. He has been bought to clinic slightly earlier to monitor his paraprotein. … Continue reading
Posted in Myeloma/paraproteins
Tagged MGUS, monoclonal gammopathy, myeloma, Paraprotein
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Case 91 – update 1
So our patient has been seen by haematology. He initially presented with shoulder pain. Following X-ray and MRI this has been shown to be due to osteoarthritis with no evidence of lytic lesions. Bone marrow had shown a normocellular marrow … Continue reading
Posted in Myeloma/paraproteins
Tagged MGUS, monoclonal gammopathy, myeloma, Paraprotein
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Case 91 – the beginning
Welcome to this week’s TeamHaem case! This week we start in general practice. A 70 year old man saw your colleague complaining of shoulder pain. Some bloods were done as he was due his ‘well man’ bloods around the same … Continue reading
Posted in Myeloma/paraproteins
Tagged MGUS, monoclonal gammopathy, myeloma, Paraprotein
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Case 75 – update 1
Thanks for everyones contributions. The following results are now back: SFLC kappa: lambda ratio: 6543. Igs and serum electrophoresis: Immuneparesis and IgA kappa paraprotein 18 B2 microglobulin 8.7. Albumin 28. Bone marrow biopsy: 66% plasma cells morphologically. Flow cytometry … Continue reading
Posted in Myeloma/paraproteins
Tagged Bone marrow, Cytogenetics, Flow cytometry, Paraprotein, serum free light chains
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Case 69 – part 3 – summary
During this short case we looked at serum protein electrophoresis. This showed a band in the gamma region and immunofixation confirmed a IgM kappa paraprotein. IgM paraproteins are commonly associated with MGUS, low grade lymphoma and rarely myeloma. Typically IgM … Continue reading
Posted in Lymphoma
Tagged electrophoresis, hyperviscosity, IgM paraprotein, Lymphoma, lymphoplasmacytic lymphoma, myeloma, Paraprotein, Waldrenstroms
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Case 69 – part 3 – the beginning
Thanks for contributing! Please use #TeamHaem in your reply on Twitter! A 69 year old gentleman presents to his GP with headache and visual blurring. Giant cell arteritis is suspected as the ESR is 120mm/hr. A serum protein electrophoresis … Continue reading
Posted in Lymphoma
Tagged electrophoresis, hyperviscosity, IgM paraprotein, Lymphoma, lymphoplasmacytic lymphoma, myeloma, Paraprotein, Waldrenstroms
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Case 62 – summary
Haematological emergencies Patient A presented with an episode of neutropenic sepsis. As a junior you should be suspicious of someone being neutropenic if they have had recent chemotherapy (usually within the past 1-2 weeks). Reviewing patients previous blood results … Continue reading
Case 62 – part B
Case B A 55 year old women attends the Haematology day unit where you are the junior reviewing emergencies. She has a background of IgG MGUS. She has noticed some difficult walking up the stairs over the past few weeks … Continue reading
Posted in Myeloma/paraproteins
Tagged Back pain, Paraprotein, spinal cord compression
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Case 50 part 3 – summary
It just goes to show that picking up on simple signs can lead to the start of a diagnostic journey. The patient with the film below (second from left) had a FBC as she had suffered from back pain and … Continue reading
Posted in Laboratory morphology, Myeloma/paraproteins
Tagged Blood film, myeloma, Paraprotein
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Case 50 part 3 – the beginning
You are reviewing the blood films from today. Can you make a diagnosis without a microscope? Please reply to us (@TeamHaem) on Twitter and always include #TeamHaem to allow others to follow your comments. Please join in the … Continue reading
Posted in Laboratory morphology, Myeloma/paraproteins
Tagged Blood film, myeloma, Paraprotein
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Case 48 – #UnofficialCSIM2 update 1
Thanks for joining the case, where as a surgical FY1 doctor you were asked to review Mr Jones, a 75 year old man who had been admitted after a fall leading to a femur fracture. The nurses were worried that … Continue reading
Posted in Myeloma/paraproteins
Tagged fracture, hypercalcaemia, myeloma, Paraprotein
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