Tag Archives: Paraprotein

Case 97 – Summary

Posted on 04/08/2018 by

This week we looked at a neuropathy presenting via the neurology team associated with a plasma cell dyscrasia. This area of haematology is often challenging! The diagnosis can be difficult and even after diagnosis there is a lack of evidence … Continue reading →

Posted in Lymphoma, Myeloma/paraproteins, Related to other specialities | Tagged , , , , , , , , , ,

Case 97 – update 3

Posted on 03/08/2018 by

Thanks for your help so far with this case. so far we know our patient is a 54 year old male who presented to clinic with distal sensory loss and a broad based gait which has been slowly progressing over … Continue reading →

Posted in Lymphoma, Myeloma/paraproteins, Related to other specialities | Tagged , , , , , , , , , ,

Case 97 – update 2

Posted on 02/08/2018 by

The bone marrow aspirate did appear to show an excess of Plasmacytoid and lymphoplasmacytoid cells. Immunophenotype results: Abnormal population: Kappa restricted B cell population = 18% of total nucleated cells. Immunophenotype: CD19+, CD5 negative, CD23 negative/wk, CD10 negative, CD103 negative, … Continue reading →

Posted in Laboratory morphology, Lymphoma, Myeloma/paraproteins, Related to other specialities | Tagged , , , , , ,

Case 97 – update 1

Posted on 30/07/2018 by

Thanks for your help so far The neurology team contact you as they have the results of the Nerve conduction studies they performed a few weeks ago these show “prolonged conduction velocities consistent with demyelination in an axonal loss pattern” … Continue reading →

Posted in Lymphoma, Myeloma/paraproteins, Related to other specialities | Tagged , , ,

Case 97 – the beginning

Posted on 29/07/2018 by

Welcome to another #TeamHaem case You are in the Haematology new patient clinic and receive a letter from the local Neurology team asking you to assess a 54 year old male who has an Ig M kappa paraprotein of 6g/dl … Continue reading →

Posted in Lymphoma, Myeloma/paraproteins, Related to other specialities | Tagged , , ,

Case 91 – summary

Posted on 29/03/2018 by

Thank you for all your contributions this week! This week we had a look at MGUS (monoclonal gammopathy of undetermined significance). Our patient was diagnosed with IgA lambda MGUS, which was monitored 6 monthly for 4 years. This then progresses … Continue reading →

Posted in Myeloma/paraproteins | Tagged , , ,

Case 91 – update 2

Posted on 28/03/2018 by

We have been monitoring our patient 6 monthly for 4 years. His para protein has been slowly rising and was 10g/l on his last visit 3 months ago. He has been bought to clinic slightly earlier to monitor his paraprotein. … Continue reading →

Posted in Myeloma/paraproteins | Tagged , , ,

Case 91 – update 1

Posted on 26/03/2018 by

So our patient has been seen by haematology. He initially presented with shoulder pain. Following X-ray and MRI this has been shown to be due to osteoarthritis with no evidence of lytic lesions. Bone marrow had shown a normocellular marrow … Continue reading →

Posted in Myeloma/paraproteins | Tagged , , ,

Case 91 – the beginning

Posted on 25/03/2018 by

Welcome to this week’s TeamHaem case! This week we start in general practice. A 70 year old man saw your colleague complaining of shoulder pain. Some bloods were done as he was due his ‘well man’ bloods around the same … Continue reading →

Posted in Myeloma/paraproteins | Tagged , , ,

Case 75 – update 1

Posted on 11/04/2017 by

Thanks for everyones contributions. The following results are now back:   SFLC kappa: lambda ratio: 6543. Igs and serum electrophoresis: Immuneparesis and IgA kappa paraprotein 18 B2 microglobulin 8.7. Albumin 28. Bone marrow biopsy: 66% plasma cells morphologically. Flow cytometry … Continue reading →

Posted in Myeloma/paraproteins | Tagged , , , ,

Case 69 – part 3 – summary

Posted on 21/12/2016 by

During this short case we looked at serum protein electrophoresis. This showed a band in the gamma region and immunofixation confirmed a IgM kappa paraprotein. IgM paraproteins are commonly associated with MGUS, low grade lymphoma and rarely myeloma. Typically IgM … Continue reading →

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Case 69 – part 3 – the beginning

Posted on 20/12/2016 by

Thanks for contributing! Please use #TeamHaem in your reply on Twitter!   A 69 year old gentleman presents to his GP with headache and visual blurring. Giant cell arteritis is suspected as the ESR is 120mm/hr. A serum protein electrophoresis … Continue reading →

Posted in Lymphoma | Tagged , , , , , , ,

Case 62 – summary

Posted on 07/08/2016 by

Haematological emergencies   Patient A presented with an episode of neutropenic sepsis.  As a junior you should be suspicious of someone being neutropenic if they have had recent chemotherapy (usually within the past 1-2 weeks).  Reviewing patients previous blood results … Continue reading →

Posted in Bone marrow failure, Myeloma/paraproteins | Tagged , , , , , ,

Case 62 – part B

Posted on 02/08/2016 by

Case B A 55 year old women attends the Haematology day unit where you are the junior reviewing emergencies.  She has a background of IgG MGUS.  She has noticed some difficult walking up the stairs over the past few weeks … Continue reading →

Posted in Myeloma/paraproteins | Tagged , ,

Case 50 part 3 – summary

Posted on 16/12/2015 by

It just goes to show that picking up on simple signs can lead to the start of a diagnostic journey. The patient with the film below (second from left) had a FBC as she had suffered from back pain and … Continue reading →

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Case 50 part 3 – the beginning

Posted on 15/12/2015 by

You are reviewing the blood films from today. Can you make a diagnosis without a microscope?     Please reply to us (@TeamHaem) on Twitter and always include #TeamHaem to allow others to follow your comments. Please join in the … Continue reading →

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Case 48 – #UnofficialCSIM2 summary

Posted on 09/11/2015 by

Thank you for joining the case. We’ve already met Mr Jones, a 75 year old man admitted following a fall to an orthopaedic ward with a fractured neck of femur. We agreed that his behaviour was new and odd and … Continue reading →

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Case 48 – #UnofficialCSIM2 update 1

Posted on 03/11/2015 by

Thanks for joining the case, where as a surgical FY1 doctor you were asked to review Mr  Jones, a 75 year old man who had been admitted after a fall leading to a femur fracture. The nurses were worried that … Continue reading →

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Case 48 – UnofficialCSIM2 – oncology week

Posted on 02/11/2015 by

Hi to all those joining us from #unofficialCSIM2. To remind our usual teamhaem-ers again – the #unofficialCSIM2 project is aimed at 4th year medical students. Whilst everyone’s input is appreciated, it would be helpful if those of you with more … Continue reading →

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Case 47 – summary

Posted on 30/10/2015 by

Thank you for all your help with this weeks case! We have had some very helpful renal input this week! This week we looked at the case of a normally fit 60year old gentleman who presented with peripheral oedema and … Continue reading →

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