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Tag Archives: thrombocytopenia
Case 100 (part D) – summary
The patient had mild thrombocytopenia and has suffered epistaxis. Epistaxis is relatively common and therefore structural causes should also be looked into. This is especially so if the nose bleeds are unilateral. There is a wide differential of why someone … Continue reading
Case 100 (part D) – update
You repeat the FBC and it shows similar results Hb 141g/l (130-180) MCV 89fl (82-98) WCC 7.5×109/l (4-11) Neutrophils 4.7×109/l (1.7-7.5) Lymphocytes 2.1×109/l (1.5-4.5) Platelets 70×109/l (150-450) Coagulation screen – normal U&E/LFT – normal Blood film: Questions What is the … Continue reading
Case 100 (part D) – the beginning
You are a GP evaluating a 12 year old boy with persistent nose bleeds. He otherwise feels well with no past medical history. He is on no medications. FBC shows: Hb 140g/l (130-180) MCV 90fl (82-98) WCC 8.5×109/l (4-11) Neutrophils … Continue reading
Posted in Inherited bleeding, Paediatric haematology, Platelet disorders
Tagged bleeding, bleeding history, epistaxis, thrombocytopenia
Case 96 – summary
Thank you for participating in our case this week. This week we have been looking at a case of JMML (Juvenile myelomonocytic leukaemia), which is a rare clonal haematopoietic disorder of childhood, characterised by the proliferation of granulocytic and monocytic … Continue reading
Case 96 – update 4
The haematology team has now taken over his care. Bone marrow aspirate has demonstrated a hypercellular marrow with left shift, and there are increased myeloid and monocyte lineages. Blast count is about 4%. There is occasional evidence of haemophagocytosis and … Continue reading
Case 96 – update 3
The blood film has been reported: – leukocytosis with neutrophilia and monocytosis, there is left shift and toxic granulation and vacuolation. Occasional primitive cells ~ 2%. No nucleated RBCs. The appearances might be reactive/infection related, and infection as well as … Continue reading
Case 96 – update 2
An USS abdomen has been performed which confirms mild hepato-splenomegaly. CXR was reported as normal. Faecal elastase, TTG, TFTs, ILGF1 all normal. You phone the haematology registrar to look at the blood film in view of the abnormal FBC. Questions: … Continue reading
Case 96 – update 1
This 13 month old boy was born at 39/40 by normal delivery. His birth weight was 2.6kg. He is normally fit and well with no significant problems and no previous hospital admissions. He is up to dates with all his … Continue reading
Posted in Paediatric haematology
Tagged anaemia, hepatosplenomegaly, monocytosis, neutrophilia, paediatrics, thrombocytopenia, weight loss
Case 81 – summary
Thank you for all the contributions to the case this week. The case We looked at a case of a 58 year gentleman who had an incidental finding of thrombocytopenia, whilst on apixaban therapy. Immediate intervention was required to stop … Continue reading
Posted in Acquired bleeding, Anticoagulation, Platelet disorders
Tagged anticoagulation, bleeding, ITP, thrombocytopenia
Case 81 – update 2
Thankfully the bleeding resolves and no surgical intervention is required The platelet count responds to IVIG, and dexamethasone 40mg given for four days. Any further investigations required? 2 week s following commencement of steroids the platelet count has fallen … Continue reading
Posted in Acquired bleeding, Anticoagulation, Platelet disorders
Tagged anticoagulation, bleeding, ITP, thrombocytopenia
Case 81 – update 1
Our followers have come up with a very comprehensive list of investigations! Our advice/investigation included stopping apixaban Checking Fbc ? Any other abnormalities/previous FBC/ clot in sample coagulation. Prolonged PT, normal aptt and fibrinogen renal and liver function HIV, hepatitis … Continue reading
Posted in Acquired bleeding, Anticoagulation, Platelet disorders
Tagged anticoagulation, bleeding, thrombocytopenia
Case 81 – the beginning
A 58 year old gentlemen has routine bloods taken at the GP surgery. He is noted to have a platelet count of 38. His doctor rings you as the haematology registrar for advise as he is on apixaban for treatment … Continue reading
Posted in Acquired bleeding, Anticoagulation, Platelet disorders
Tagged anticoagulation, thrombocytopenia
Case 61 – summary
Thank you for all your help this week! This week we looked at a case of childhood ITP. Our patient presented with easy bruising over a 3 week period, and had had a minor urti the previous month. The patient … Continue reading
Posted in Acquired bleeding, Platelet disorders
Tagged bleeding, easy bruising, iron deficiency, ITP, microcytosis, thrombocytopenia
Case 61 – update 2
So time for another update! Our patient has been started on oral iron for a iron deficiency anaemia. Given that she only has some bruising and a slight petechial rash the decision has been made to monitor her, but not … Continue reading
Posted in Acquired bleeding, Platelet disorders
Tagged bleeding, easy bruising, iron deficiency, ITP, microcytosis, thrombocytopenia
Case 61 – update 1
What have we found out so far? We have a 15 year old girl who has presented with a few week history of easy bruising. Blood tests have shows a microcytic anaemia with ferritin of 5 and a thrombocytopenia with … Continue reading
Posted in Acquired bleeding, Platelet disorders
Tagged bleeding, easy bruising, microcytosis, thrombocytopenia
