Tag Archives: Von willebrands disease

Case 64 – part 2 – summary

The main aim of this case was to remember that the coagulation screen alone is not suitable for ruling out a bleeding disorder. The most common inherited bleeding disorder frequently will have a normal clotting screens. Indiscriminate clotting screens are … Continue reading

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Case 64 – part 2b

Further questioning of our pre-operative patient reveals she has easy bruising without trauma and has required cauterisation for epistaxis in the past. She bled after a tooth was removed and had to see the dentist following the procedure due to … Continue reading

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Case 64 – part 1 – summary

We started with a 72 year old gentleman who was having an elective pacemaker insertion. He had an isolated prolonged APTT and we have previously used the following flow chart to make a diagnosis:   It should be remembered that … Continue reading

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Case 33 – summary

Von Willebrands disease The aim of this case was to identify a patient with Von Willebrands disease and arrange appropriate investigations. Von Willebrand disease (vWD) is a common, inherited, genetically and clinically heterogeneous hemorrhagic disorder caused by a deficiency or … Continue reading

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Case 33 – update 2

Thanks for all the tweets regarding further investigations! In the “real world” I guess we have to prioritise the investigations required – think of our budget and workload! A few have suggested von willebrand screen, which seems the most obvious … Continue reading

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Case 26 – update 3

To summarise: 38 year old man with incidental finding of a prolonged APTT on pre-op bloods. History: major orthopaedic surgery without bleeding. Some bleeding post dental extraction but no intervention needed. No family history. Investigations: no LA. Factor assays show … Continue reading

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Case 14 – update 4

Factor levels are undertaken – results show a reduced factor VIII levels, however all other factors are within normal range. Von willibrands screen has therefore been requested. Are there any other causes of reduced factor VIII levels in this patient? Consider the … Continue reading

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